Effects of the use of carvedilol in dilated cardiomyopathy in pediatric age
Abstract
Introduction: dilated cardiomyopathy is the most common worldwide cardiomyopathy. In pediatric patients, the annual incidence is 0.5-1.2 cases per 100,000, with 8-12 times more common presentation in infants (4.4 per 100,000) than in older children. Considering the limited prognosis of long-term cardiac transplantation and absence of adequate pediatric donors, all strategies that seek to improve current medical treatments and investigate alternative therapeutic options are justified.
Development: a bibliographic review was carried out with the aim of knowing the use effects of carvedilol in dilated in pediatric age. Dilated cardiomyopathy is characterized by a massive cardiomegaly secondary to wide enlarged ventricles. The prevalence in the child population is 36.5 per 100 000 live births, aggressive treatment of heart failure can make a temporary remission, but relapses are common and patients that tend to become resistant to the usual medication. Conclusions: the introduction of carvedilol in the pediatric treatment of these diseases is relatively new, and requires a study of the issue further.
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