Ketonuria in the diagnosis of acute appendicitis

Authors

  • Eva Alejandrina Lluiz Hernández
  • Pedro Rafael Casado Méndez
  • Rafael Salvador Santos Fonseca
  • Onelia Méndez Jiménez
  • Irene Luisa del Castillo Remón
  • Dolores Labrada González

Abstract

Introduction: the high prevalence of acute appendicitis, the lack of reliable predictors of this disease and the fact that in the bodies ward of hospital is not routinely measured the presence of ketone bodies in the urine of patients, it is necessary to verify the little evidence available about ketosis as a predictor of acute appendicitis.

Objective: to determine the possible reliability of ketonuria in the diagnosis of acute appendicitis.

Method: a quantitative, prospective, observational and descriptive study with analytical phases was performed at the General Surgery Service of the "Celia Sánchez Manduley" Provincial Surgical Clinic Hospital in Manzanillo, Granma, from December 2014 to April 2015.The universe consisted of 362 patients diagnosed with acute appendicitis. Each patient's urine was analyzed by means of test strips and the Imbert reaction to identify ketone bodies. A tabulation of the possible ketosis causes was carried out, which were quantified with the difference test of proportions. The results were presented in tables and graphs.

Results: taking into account all the patients diagnosed with acute appendicitis, 21 % presented ketosis. No statistically significant differences were found between the detection of ketosis by test strips and the reaction of Imbert: both tests showed specificity of 90% and low sensitivity (21 %) and effectiveness (37 %); in most cases it was possible to attribute the presence of ketone bodies to known causes

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Author Biographies

Eva Alejandrina Lluiz Hernández

Especialista de Primer Grado en Bioquímica Clínica. Profesor Asistente. Universidad de Ciencias Médicas “Celia Sánchez Manduley”, Manzanillo. Granma, Cuba

Pedro Rafael Casado Méndez

Especialista de Primer Grado en Cirugía General. Especialista de Segundo Grado en Medicina General Integral. Profesor Instructor. Investigador Agregado. Hospital Clínico Quirúrgico Provincial “Celia Sánchez Manduley”, Manzanillo. Granma, Cuba

Rafael Salvador Santos Fonseca

Doctor en Medicina. Policlínico Docente “Luis Enrique de la Paz Reina”, Yara. Granma, Cuba

Onelia Méndez Jiménez

Máster en Metodología de la Investigación Educativa. Licenciada en Educación. Especialidad Historia. Profesor Auxiliar. Universidad de Ciencias Médicas “Celia Sánchez Manduley”, Manzanillo. Granma, Cuba

Irene Luisa del Castillo Remón

Máster en Educación Superior. Licenciada en Educación. Especialidad Biología. Profesor Auxiliar. Universidad de Ciencias Médicas “Celia Sánchez Manduley”, Manzanillo. Granma, Cuba

Dolores Labrada González

Licenciada en Educación. Especialidad Inglés. Profesor Asistente. Universidad de Ciencias Médicas “Celia Sánchez Manduley”, Manzanillo. Granma, Cuba

Published

2016-11-04

How to Cite

1.
Lluiz Hernández EA, Casado Méndez PR, Santos Fonseca RS, Méndez Jiménez O, del Castillo Remón IL, Labrada González D. Ketonuria in the diagnosis of acute appendicitis. Mediciego [Internet]. 2016 Nov. 4 [cited 2024 Nov. 21];23(2):29-36. Available from: https://revmediciego.sld.cu/index.php/mediciego/article/view/687

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