Diffuse large B lymphoma cell lymphoma

Abstract

Introduction: diffuse B-cell lymphoma is the most common type of non-Hodgkin lymphoma in adults. It is characterized by its aggressiveness and wide location. Usually, the first sign of its presence is a rapidly growing mass, with some lymph nodes. Fever, weight loss and profuse night sweats may also occur.

Objective: a case of diffuse large B-cell lymphoma is presented which by its atypical presentation form (soft-tissue lymphoma with internal organs), is of interest to the specialists.

Case presentation: female patient, 65 years old, dark skin color and a history of arterial hypertension. She came to the clinic for presenting a painful tumor mass in the left region of the back and weight loss. Did not present cough, dyspnea or other respiratory symptoms. During the physical examination, a hard, non-painful and immovable mass of approximately 12 x 12 cm was palpated on the left posterolateral thoracic wall. In the immunohistochemical examination the presence of diffuse large B-cell lymphoma (stage IV) was confirmed.

Discussion: despite the atypical presentation of the disease, the immunohistochemical diagnosis and the involvement of other organs (ribs and pleura) are data consistent with what has been reported in the literature.

Conclusions: in the presence of a painful tumor mass and weight loss without other symptoms, diffuse large B-cell lymphoma with atypical presentation should be considered as possible diagnosis