Luminal invasive ductal carcinoma A in a man. Case report
Keywords:
brca 2 protein; breast ductal carcinoma; case reports; doppler ultrasonography; fine-needle biopsy; male breast neoplasmsAbstract
Introduction: male breast cancer is rare, accounting for only 1.00% of all breast neoplasms diagnosed worldwide. This low incidence leads to limited knowledge about the characteristics of the disease and, consequently, delayed diagnosis, which negatively affects prognosis.
Objective: to describe luminal A invasive ductal carcinoma in a male patient.
Case presentation: a 60-year-old white man with hypertension and a family history of maternal breast cancer presented with a painless retroareolar nodule in the left breast. Ultrasonography revealed a lesion with irregular margins and internal vascularization, suggestive of malignancy. Fine-needle aspiration biopsy confirmed invasive ductal carcinoma. Histopathological examination showed proliferation of infiltrating neoplastic epithelial cells. Immunohistochemical analysis demonstrated positivity for estrogen and progesterone receptors (98.00%), HER2 negative, and a Ki-67 index of 10.00%. The tumor was classified as the luminal A subtype. The patient underwent surgical treatment, with favorable clinical evolution.
Conclusions: the limited tumor development, absence of palpable lymphadenopathy, presence of positive hormonal receptors, and a low Ki-67 index indicated a favorable prognosis. Due to the scarcity of national reports on this uncommon neoplasm in men, genetic studies are important in individuals with suspicious symptoms and a family history of the disease. This report confirms that imaging techniques, as well as histopathological and immunohistochemical analyses, are essential for timely and accurate diagnosis.
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