Clinical, epidemiological and histological profile of patients with oral squamous cell carcinoma
Keywords:
mouth neoplasm, lips neoplasm, carcionma; squamous cell, tabacco use disorderAbstract
Introduction: squamous cell carcinoma is the most common dental malignancy and has the capacity for local destructive growth and distant metastasis.
Objective: to characterize patients with oral squamous cell carcinoma in the northern territory of the Ciego de Ávila province.
Methods: a cross-sectional descriptive study was carried out in 51 patients diagnosed with oral squamous cell carcinoma who met the inclusion criteria, who were treated at the maxillofacial surgery service of the General Teaching Hospital of Morón. Ethical principles were met.
Results: prevailed in the male sex (76.47 %), in the group of 55 to 74 years (78.43 %), in the lower lip as a location (23.53 %), the clinical stage III (45.10 %) and lesions greater than four centimeters (72.55%). Almost all smoked (92.00%) and more than half consumed alcohol (55.00 %). 42.00 % had a personal pathological history of suffering from cancer and 36.00% had other associated diseases. Well-differentiated (50.98%) and moderately differentiated (29.41 %) lesions were the most frequent, especially in the age group of 55 to 74 years.
Conclusions: the largest number of patients were male and were between 55 and 74 years of age. The most frequent tumor location was in the lower lip. As a predisposing factor to oral cancer, tobacco use predominated. Most of the patients were found in clinical stage III and were classified as well-differentiated carcinomas.
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Zaldívar-Aguilera L, Leyva-Matos AT, Matos-Serrano O, Rodríguez-Nápoles KC. Caracterización del carcinoma epidermoide bucal. Hospital Clínico-Quirúrgico de Holguín, 2018. Congreso Interacional Estomatología 2020 [Internet]. 2020 [citado 4 Dic 2021]:[aprox. 12 p.]. Disponible en: http://estomatologia2020.sld.cu/index.php/estomatologia/2020/paper/view/149/342
Mourelle-González A. Estudio de supervivencia y recidiva del Carcinoma epidermoide Oral y de Orofaringe [Internet]. Santiago de Compostela: Universidad de Santiago de Compostela; 2019 [citado 4 Dic 2021]. Disponible en: https://minerva.usc.es/xmlui/bitstream/handle/10347/20739/rep_1994.pdf?sequence=1&isAllowed=y
Martín-Rodríguez O, Betancourt-Valladares M, García-Ranero AB, Gianse-Paz L. Pronóstico de incidencia y mortalidad del cáncer bucal en la provincia Ciego de Ávila. Rev Cubana Estomatol [Internet]. 2017 [citado 4 Dic 2021];54(3):[aprox. 11 p.] Disponible en: http://www.revestomatologia.sld.cu/index.php/est/article/view/1332/638
Jaroid-Ferrer U. Nuevo score pronóstico global del carcinoma escamoso de cavidad oral en estadios localizados [Internet]. Zaragoza: Universidad de Zaragoza; 2017 [citado 4 Dic 2021]. Disponible en: https://dialnet.unirioja.es/servlet/tesis?codigo=202230
García-San Juan CM, Salas-Rodríguez MS, Gil-Milá JM. Algunas consideraciones sobre etiología y fisiopatogenia del carcinoma epidermoide bucal. MediSur [Internet]. 2018 [citado 4 Dic 2021];16(1):63-75. Disponible en: http://scielo.sld.cu/pdf/ms/v16n1/ms10116.pdf
Ministerio de Salud Pública (Cuba). Anuario Estadístico de Salud 2019 [Internet]. La Habana: Dirección Nacional de Registros Médicos y Estadísticas de Salud; 2020 [citado 4 Dic 2021]. Disponible en: https://files.sld.cu/bvscuba/files/2020/05/Anuario-Electr%c3%b3nico-Espa%c3%b1ol-2019-ed-2020.pdf
Asociación Médica Mundial. Declaración de Helsinki de la AMM. Principios éticos para las investigaciones médicas en seres humanos. Ratificada en la 64ª Asamblea General, Fortaleza, Brasil, octubre 2013. Helsinki: 18ª Asamblea Mundial; 1964 [citado 4 Dic 2021]. Disponible en: http://www.anmat.gov.ar/comunicados/HELSINSKI_2013.pdf
Hermida-Rojas M, González-Docando YE, Borroto-Alcorta DC. Epidemiología del cáncer bucal en la provincia Ciego de Ávila. Estudio de quince años (1991 a 2005). MediCiego [Internet]. 2007 [citado 4 Dic 2021];13(1):[aprox. 6 p.]. Disponible en: https://revmediciego.sld.cu/index.php/mediciego/article/download/2286/3376
Torres-Morales Y, Rodríguez-Martín O, Rodríguez-Rodríguez N, Viera-Morales KB, Díaz-Hernández MJ, Marichal-Martínez YA. Factores pronósticos del carcinoma epidermoide bucal. MediCiego [Internet]. 2020 [citado 4 Dic 2021];26(2):[15 aprox.]. Disponible en: http://www.revmediciego.sld.cu/index.php/mediciego/article/download/1273/3060
Saleem Z, Shaikh AH, Zaman U, Ahmed S, Majeed MM, Kazmi A, et al. Estimation of salivary matrix metalloproteinases- 12 (MMP- 12) levels among patients presenting with oral submucous fibrosis and oral squamous cell carcinoma. BMC Oral Health [Internet]. 2021 [citado 4 Dic 2021];21(1):[aprox 8 p.]. Disponible en: https://bmcoralhealth.biomedcentral.com/track/pdf/10.1186/s12903-021-01571-7
Faustino SES, Tjioe KC, Assao A, Pereira MC, Carvalho AL, Kowalski LP, et al. Association of lymph vessel density with occult lymph node metastasis and prognosis in oral squamous cell carcinoma. BMC Oral Health [Internet]. 2021 [citado 4 Dic 2021];21(1):[aprox 9 p.]. Disponible en: https://bmcoralhealth.biomedcentral.com/track/pdf/10.1186/s12903-021-01459-6
Corrales-Reyes I, Cruz-Sánchez V, Mejia C. Carcinoma epidermoide intraoral y factores de riesgo asociados: un estudio de casos y controles. Rev. Cub. Med. Mil [Internet]. 2021 [citado 4 Dic 2021];50(3):[aprox 15 p.]. Disponible en: http://scielo.sld.cu/pdf/mil/v50n3/1561-3046-mil-50-03-e1401.pdf
Gallegos-Hernández JF. Factores clínicos e histológicos que repercuten en el pronóstico de los pacientes con cáncer de la cavidad oral. An Orl Mex [Internet]. 2017 [citado 4 Dic 2021];62(3):197-208. Disponible en: https://www.medigraphic.com/pdfs/anaotomex/aom-2017/aom173f.pdf
González-Umpiérrez N, Beovide-Cortegoso V. Perfil del Carcinoma Oral de Células Escamosas en el Laboratorio de Anatomía Patológica de la Facultad de Odontología de la Universidad de la República, período 1982-2015. Odontoestomatología [Internet]. 2020 [citado 4 Dic 2021];22(36):34-43. Disponible en: http://www.scielo.edu.uy/pdf/ode/v22n36/1688-9339-ode-22-36-34.pdf
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