Behavior of the Adrenal Hyperplasia Congenital Program in the southern part of Ciego de Avila´s province. 2005 to 2011
Abstract
The Adrenal Hyperplasia Congenital includes a group of enzyme disorders of the adrenal gland that entail to an alteration in the synthesis of Hydrocortisone and Aldosterone, with accumulation of androgen precursors. It was carried out a, retrospective observational descriptive study of evaluation character about the development of the program since its implementation in October 2005 until December 2011, number of elevated results, of the municipalities where it is offered the services of the SUMA laboratory of the Provincial Teaching General Hospital "Dr. Antonio Luaces Iraola". There were analyzed 14985 samples of dried blood of newborn on filter paper in the southern part of Ciego de Avila´s Province, in addition to all children of the different areas of the province who were hospitalized in this hospital to the fifth day of being born. The statistical analysis was carried out through the package of statistical information SPSS to Windows XP. As measure of summarizing information there were used the frequency and percentage distributions. It was demonstrated the interrelation between the high values of elevated results of 17 - OH progesterone, Infant Low Birth Weight and the gestational age before 37 weeks.Downloads
References
Pang S. Congenital adrenal hyperplasia. Endocrinol Metab Clin North Am. 1997; 26(4): 853-91.
Soriano Guillén L, Velázquez de Cuéllar Paracchi M. Hiperplasia suprarrenal congénita. Pediatría Integr [Internet]. 2007 [citado 5 Mar 2013]; 11(7): [aprox. 9 p.]. Disponible en: http://www.sepeap.org/imagenes/secciones/Image/_USER_/PI(1).pdf#page=3
Zaldívar Ochoa JR, Rodríguez Carballo A, Quesada Cortés M, Navarro Lautén A, Martínez Álvarez M. Hiperplasia adrenal congénita clásica. Tratamiento médico y quirúrgico. MEDISAN [Internet]. 2010; 14(6):[aprox. 6 p.]. Disponible en: http://scielo.sld.cu/scielo.php?pid=S1029-30192010000600017&script=sci_arttext
Richmond Padilla E. Hiperplasia suprarrenal congénita. Acta Pediátr Costarric [Internet]. 2009 [citado 5 Mar 2013]; 21(2):73-75. Disponible en: http://www.binasss.sa.cr/revistas/apc/v21n2/art1.pdf
Hiperplasia suprarrenal congénita. Medline Plus [Internet]. 2012 [actualizada 27 Feb 2013; citado 5 Mar 2013] [aprox. 3 pantallas]. Disponible en: http://www.nlm.nih.gov/medlineplus/spanish/ency/article/000411.htm
17-OH progesterona. Medline Plus [Internet]. 2012 [actualizado 27 Feb 2013; citado 5 Mar 2013]. [aprox. 3 pantallas]. Disponible en: http://www.nlm.nih.gov/medlineplus/spanish/ency/article/003713.htm
Pang S, Wallace MA, Hofman L, Thuline HC, Dorche C, Lyon ICT, Dobbins RH, Kling S, et al. Worldwide experience in newborn screening for classical congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Pediatrics. 1988; 81: 866-74.
Cattani OA, Reyes ML, Azócar M, Soto MJ, Romeo E, Valdivia L, et al. Medición de 17-OH progesterona sanguínea en recién nacidos chilenos: Antecedentes para implementar un programa de detección neonata de hiperplasia suprarrenal congénita. Rev Méd Chile [Internet]. 2000 [citado 5 Mar 2013]; 128(10):1113-1118. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872000001000006&lng=es
Coto Rodeiro R, Varona Sánchez JA, Borrego López JA, Formoso Martín LE. Resultados de la pesquisa de hiperplasia adrenal congénita en recién nacidos. Rev Cubana Obstet Ginecol [Internet]. 2011 [citado 18 Feb 2013]; 37(2):136-146. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-600X2011000200003&lng=es