Clinical and Therapeutic Characterization of Postpartum Hemorrhage in Patients at Sermesa Hospital, Masaya, Nicaragua

Authors

Keywords:

maternal mortality; morbidity and mortality indicators; postpartum hemorrhage; uterine inertia; uterotonic agents

Abstract

Introduction: postpartum hemorrhage is one of the leading causes of maternal morbidity and mortality worldwide.

Objective: to characterize patients with postpartum hemorrhage from an epidemiological, clinical, and therapeutic perspective at Sermesa Hospital, Masaya, from February 2024 to June 2025.

Methods: a mixed-method, descriptive cross-sectional study was conducted in 72 patients with postpartum hemorrhage. Epidemiological and obstetric variables (parity and mode of delivery), clinical variables (type, timing, and cause of hemorrhage), and the type of treatment administered were analyzed. Factors influencing treatment selection and the level of adherence to clinical protocols were assessed through specialists’ opinions obtained via semi-structured interviews. Data were collected from medical records and summarized as percentages.

Results: the 25–34 years age group predominated (51.40 %), with a higher proportion of patients from rural areas (56.00 %). Most cases corresponded to immediate postpartum hemorrhage (94.40 %), in which uterine atony was the most frequent cause. Initial management was based on the use of uterotonic agents and uterine massage, while surgical intervention was less frequently required. Adequate adherence to clinical protocols was observed in most cases. The choice of treatment was influenced by the patients’ clinical condition, the cause of hemorrhage, the clinical experience of the medical staff, the availability of resources, and the response to initial management.

Conclusions: conservative medical management predominated, was effective in most cases, and showed adequate adherence to institutional protocols, providing valuable local evidence to strengthen clinical practice and reduce maternal morbidity and mortality.

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Author Biographies

José Carlos Suazo Alfaro, Docente a tiempo completo de la Universidad Central de Nicaragua. Managua, Nicaragua.

Médico General. 

Kevin Enmanuel García Vanegas, Universidad Central de Nicaragua. Managua, Nicaragua.

Médico General. Coordinador de la carrera de Médico General. 

Marbet Gabriela Mendoza Cajina, Universidad Central de Nicaragua. Managua, Nicaragua.

Médico General. Coordinador de la carrera de Médico General. 

References

1. Mohamed TAEH, Chandraharan E. Recognition and management of postpartum hemorrhage. Matern Fetal Med [Internet]. 2025 [citado 21 Feb 2026];7(1):29-37. Disponible en: https://pmc.ncbi.nlm.nih.gov/articles/PMC12222976/pdf/mfm-7-29.pdf

2. Fitzgerald I, Corcoran P, McKernan J, Connell RO, Greene RA. Trends, causes and factors associated with primary Postpartum Haemorrhage (PPH) in Ireland: A review of one million hospital childbirths. Eur J Obstet Gynecol Reprod Biol [Internet]. 2024 [citado 21 Feb 2026];301:258-63. Disponible en: https://cora.ucc.ie/server/api/core/bitstreams/c901bac4-671d-4d26-a4c5-276284f93d5e/content

3. Briones-Garduño JC. Progresos en el control de la hemorragia posparto: una revisión semisistemática. Ginecol Obstet Mex [Internet]. 2025 [citado 6 May 2026];93(4):152-63. Disponible en: https://www.scielo.org.mx/pdf/gom/v93n4/0300-9041-gom-93-04-152.pdf

4. Rivera-Fumero S, Chacón-González C, González-Chavarría A. Hemorragia posparto primaria: diagnóstico y manejo oportuno. Rev Medica Sinerg [Internet]. 2020 [citado 6 May 2026];5(6):e512. Disponible en: https://www.medigraphic.com/pdfs/sinergia/rms-2020/rms206i.pdf

5. Nucamendi-Solis E, Chávez-Reyes JM, Long-Morales NJ, Hernández-Gamboa LE, López-Cancino SA. Prevención de hemorragia posparto durante la cesárea mediante ligadura de las arterias uterinas en pacientes con factores de riesgo. Ginecol Obstet Mex [Internet]. 2024 [citado 2 May 2026];92(2):52-9. Disponible en: https://www.scielo.org.mx/pdf/gom/v92n2/0300-9041-gom-92-02-52.pdf

6. Solís-Blandón SP. Manejo de la hemorragia posparto de acuerdo a normativa 109 aplicada en el servicio de Gineco-obstetricia del Hospital Escuela Oscar Danilo Rosales Arguello, durante Julio 2017 a diciembre 2020. [Internet]. León: Universidad Nacional Autónoma de Nicaragua; 2020 [citado 24 Abr 2026]. Disponible en: http://riul.unanleon.edu.ni:8080/jspui/bitstream/123456789/8206/1/245564.pdf

7. Mercado-Parrales EA. Cumplimiento del protocolo para el manejo de hemorragia posparto en pacientes ingresadas en sala de puerperio patológico del Hospital Primario Augusto Cesar Sandino, Municipio El Jícaro, Nueva Segovia, durante 2019-2020 [Internet]. Managua: Universidad Nacional Autónoma de Nicaragua; 2021 [citado 24 Abr 2026]. Disponible en: https://repositorio.unan.edu.ni/id/eprint/15022/1/15022.pdf

8. Asociación Médica Mundial. Declaración de Helsinki de la AMM. Principios éticos para las investigaciones médicas en seres humanos. Ratificada en la 75th WMA General Assembly, Helsinki, Finland, october 2024 [Internet]. Helsinki: 18ª Asamblea Mundial; 1964 [citado 29 Oct 2025]. Disponible en: https://www.wma.net/policies-post/wma-declaration-of-helsinki/

9. Amanuel T, Dache A, Dona A. Postpartum hemorrhage and its associated factors among women who gave birth at Yirgalem General Hospital, Sidama regional state, Ethiopia. Health Serv Res Manag Epidemiol [Internet]. 2021 [citado 29 Oct 2025];8:1-7. Disponible en: https://pmc.ncbi.nlm.nih.gov/articles/PMC8640320/pdf/10.1177_23333928211062777.pdf

10. Bello-Álvarez LM, Fernández-Félix BM, Allotey J, Thangaratinam S, Zamora J. Effects of maternal education on maternal and perinatal outcomes: An individual participant data meta-analysis of 2 356 402 pregnancies. Int J Gynaecol Obstet [Internet]. 2025 [citado 24 Abr 2026];172(2):886-95. Disponible en: https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1002/ijgo.70401

11. Muñoz-De la Torre RJ, Córdova-Merino TI, Mendoza-Vilcahuaman J, Toral-Santillán EJ, Carbajal-Morán H, Márquez-Camarena FJ. Causas asociadas con hemorragia primaria posparto en mujeres andinas de Perú. Ginecol Obstet Mex [Internet]. 2024 [citado 24 Abr 2026];92(9):364-74. Disponible en: https://www.scielo.org.mx/pdf/gom/v92n9/0300-9041-gom-92-09-364.pdf

12. Nuli Nuryanti Zulala, Sunarti. Parity with risk and increased incidence of postpartum hemorrhage. PJMHS [Internet]. 2021 [citado 24 Abr 2026];15(2):552-54. Disponible en: https://pjmhsonline.com/2021/feb/552.pdf

13. Wormer KC, Jamil RT, BryanT SB. Postpartum hemorrhage. StatPearls [Internet]. 2024 [citado 24 Abr 2024]. Disponible: https://www.ncbi.nlm.nih.gov/books/NBK499988/

14. Gallos I, Williams H, Price M, Pickering K, Merriel A, Tobias A, et al. Uterotonic drugs to prevent postpartum haemorrhage: a network meta-analysis. Health Technol Assessm [Internet]. 2019 [citado 24 Abr 2026];23(9):[aprox. 8 p.]. Disponible en: http://library.snls.org.sz/archive/doc/litarch/2c/a3/ukhta2309_NBK537861/abs3.pdf

15. Serna-Muñoz R, Ramírez-Valencia MF, Gómez-Santillán JA, Figueroa-Caballero MF, Alarcón-Trejo MF. Estrategias en la prevención y manejo de la hemorragia posparto: uso de uterotónicos. An Med ABC [Internet]. 2025 [citado 24 Abr 2026];70(4):307-18. Disponible en: https://analesmedicosabc.com/wp-content/uploads/2025/04/amhabc_25_70_4_307-318.pdf

16. Escobar MF, Nassar AH, Theron G, Barnea ER, Nicholson W, Ramasauskaite D, et al. FIGO recommendations on the management of postpartum hemorrhage 2022. Int J Gynaecol Obstet [Internet]. 2022 [citado 24 Abr 2026];157(Suppl 1):3-50. Disponible en: https://pmc.ncbi.nlm.nih.gov/articles/PMC9313855/pdf/IJGO-157-3.pdf

‌17. Ministerio de Salud (Nicaragua). Normativa 109: protocolos para la atención de las complicaciones obstétricas. 2a ed [Internet]. Managua: Ministerio de Salud; 2018 [citado 24 Abr 2026]. Disponible en: https://platform.who.int/docs/default-source/mca-documents/policy-documents/guideline/NIC-MN-32-01-GUIDELINE-2018-esp-Normativa-109--Protocolos-para-la-atenci%C3%B3n-de-las-complicaciones-obst%C3%A9tricas--2018.pdf

Published

2026-05-25

How to Cite

1.
Suazo Alfaro JC, García Vanegas KE, Mendoza Cajina MG. Clinical and Therapeutic Characterization of Postpartum Hemorrhage in Patients at Sermesa Hospital, Masaya, Nicaragua. Mediciego [Internet]. 2026 May 25 [cited 2026 May 31];32:e4312. Available from: https://revmediciego.sld.cu/index.php/mediciego/article/view/4312

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